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Year : 2016  |  Volume : 5  |  Issue : 3  |  Page : 202-204

Isolated central hypothyroidism presenting with severe cholestasis, hepatosplenomegaly, and pallor: A case report and review of literature

1 Department of Pediatric Medicine, Division of Neonatology, Medical College, Kolkata, West Bengal, India
2 Department of Pediatric Medicine, Medical College, Kolkata, West Bengal, India

Correspondence Address:
Dr. Arijit Bhowmik
6, Kulada Roy Lane, Khagra, Murshidabad - 742 103, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2249-4847.191268

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Prolonged neonatal jaundice has been previously reported in neonates with congenital hypothyroidism. Isolated central hypothyroidism is a rare disease which may be missed by newborn screening programs. Here, we report a case of isolated central hypothyroidism presenting with neonatal hyperbilirubinemia, anemia, and hepatosplenomegaly, which showed marked improvement with levothyroxine supplementation.

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