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LETTER TO EDITOR
Year : 2020  |  Volume : 9  |  Issue : 3  |  Page : 227

Loss of both eyes from endogenous endophthalmitis in a term neonate with pseudomonas sepsis


Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

Date of Submission22-May-2020
Date of Decision24-Jun-2020
Date of Acceptance28-Jun-2020
Date of Web Publication07-Aug-2020

Correspondence Address:
Prof. Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad. P.O. Box: 55302, Baghdad
Iraq
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jcn.JCN_75_20

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How to cite this article:
Al-Mendalawi MD. Loss of both eyes from endogenous endophthalmitis in a term neonate with pseudomonas sepsis. J Clin Neonatol 2020;9:227

How to cite this URL:
Al-Mendalawi MD. Loss of both eyes from endogenous endophthalmitis in a term neonate with pseudomonas sepsis. J Clin Neonatol [serial online] 2020 [cited 2020 Sep 25];9:227. Available from: http://www.jcnonweb.com/text.asp?2020/9/3/227/291650



Sir,

I read with an interest the case report by Lugga et al.[1] published in the April–June 2020 issue of the Journal of Clinical Neonatology. They described a case of bilateral visual loss due to endogenous endophthalmitis in a term Nigerian neonate with Pseudomonas sepsis. Lugga et al.[1] excluded certain predisposing factors to that clinical deterioration, namely, prolonged rupture of membranes, features of asphyxia at birth, history of trauma, and the application of traditional medications to the eye.[1] However, they did not attempt to exclude immunocompromised status, particularly infection with human immunodeficiency virus (HIV) as a major risk factor for the escalating ophthalmic damage caused by Pseudomonas aeruginosa.[2] It is explicit that Nigeria is among Sub-Saharan countries seriously challenging HIV epidemic. The published data pointed out to the substantial HIV seropositivity rate (3.7%) among Nigerian pregnant women who earlier tested negative in an antenatal clinic.[3] Regrettably, Lugga et al.[1] did not take into consideration exploring HIV status in the studied neonate and mother. Hence, some form of vertical HIV transmission contributing to the escalating Pseudomonas sepsis and complete blindness in the case in question must not be overlooked

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Lugga AS, Ibrahim N, Ibrahim AO, Paret SG. Loss of both eyes from endogenous endophthalmitis in a term neonate with pseudomonas sepsis. J Clin Neonatol 2020;9:152-5.  Back to cited text no. 1
  [Full text]  
2.
Lazzeri D, Lazzeri S, Figus M, Nardi M, Pantaloni M, Agostini T. Immunocompromise as major risk factor for necrotising infections of orbital and ocular adnexa caused by Pseudomonas aeruginosa. Orbit 2010;29:373-6.  Back to cited text no. 2
    
3.
Ejikunle SD, Mbachu II, Okeudo C, Dike E, Ejikem E. Incident HIV infection and perinatal transmission rates among HIV negative pregnant women who retested in labor in a tertiary health centre, South East Nigeria. Niger J Clin Pract 2019;22:1341-8.  Back to cited text no. 3
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