Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Users Online: 295
 
About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Advertise Login 
     
CASE REPORT
Year : 2020  |  Volume : 9  |  Issue : 2  |  Page : 146-148

Hemolytic disease of the newborn due to anti-e


1 Department of Medical Laboratory Sciences, Faculty of Health Professions, Al-Quds University, Jerusalem; Department of Laboratory and Blood Bank, Yaser Arafat Hospital, Palestinian Ministry of Health, Salfit, State of Palestine
2 Department of Laboratory and Blood Bank, Yaser Arafat Hospital, Palestinian Ministry of Health, Salfit, State of Palestine

Correspondence Address:
Dr. Hammam A H. Ali
Department of Medical Laboratory Sciences, Faculty of Health Professions, Al-Quds University, Jerusalem; Department of Laboratory and Blood Bank, Yaser Arafat Hospital, Palestinian Ministry of Health, Salfit, State of Palestine

Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jcn.JCN_102_19

Rights and Permissions

In Palestine, antibody screening is done antenatally only for pregnant women who are Rh-D negative. However, we report the first hemolytic disease of the newborn (HDN) due to anti-e in Palestine, illustrating the importance of alloantibodies other than anti-D as a cause of HDN. A pregnant woman had e-antigen negative and her blood group was B positive developed alloantibody against her infant erythrocyte e-antigen that lead to severe jaundice due to fetal erythrocyte destruction by this maternal alloantibody. Postnatal workup for the severe hyperbilirubinemia indicated that the newborn' erythrocytes were sensitized by the maternal anti-e alloantibody. Furthermore, the positive direct Coombs test was reported. This case highlights the importance of antibody screening for all pregnant women irrespective of the D antigen status to detect and manage erythrocyte alloimmunization to any other clinically significant blood group antigens.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
  Search Pubmed for
  Search in Google Scholar for
Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed266    
    Printed14    
    Emailed0    
    PDF Downloaded56    
    Comments [Add]    

Recommend this journal