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Year : 2019  |  Volume : 8  |  Issue : 3  |  Page : 180-182

Term neonate with necrotizing enterocolitis and prothrombin mutation

Department of Pediatric Surgery, Yale School of Medicine, New Haven, CT, USA

Correspondence Address:
Dr. Samuel Morrison Miller
111 Park Street, Apt 8T, New Haven, CT 06511
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jcn.JCN_33_19

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The pathophysiology of necrotizing enterocolitis (NEC) in term neonates is unknown. A 37-week-old coagulopathic newborn with NEC was taken to the operating room for exploratory laparotomy and was found to have intermittent areas of necrosis from the cecum through the transverse colon. Right hemicolectomy was performed with end ileostomy. Genetic testing at 9 months of age revealed a prothrombin G20210A mutation. Hypercoagulation workup should be considered for term neonates found to have NEC without a clear etiology.

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