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Year : 2019  |  Volume : 8  |  Issue : 1  |  Page : 28-33

Assessing the use of pulse oximetry screening for critical congenital heart disease in asymptomatic term newborns

1 Department of Pediatrics, Hatyai Medical Education Center, Pediatric Cardiology Unit, Hatyai Hospital, Songkhla, Thailand
2 Department of Pediatrics, Hatyai Medical Education Center, Neonatal Intensive Care Unit, Hatyai Hospital, Hatyai, Songkhla, Thailand
3 Division of Physics, School of Science, Walailak University, Nakhon Si Thammarat, Thailand

Correspondence Address:
Dr. Suwan Danworapong
Department of Pediatrics, Hatyai Medical Education Center, Pediatric Cardiology Unit, Hatyai Hospital, 182 Rattakarn Road, Songkhla 90110
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jcn.JCN_79_18

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Background: Even though pulse oximetry screening (POS) is widely used for the early detection of critical congenital heart disease (CCHD) in unrecognized newborns, the missing cases of CCHD are still found in our practice. Aims: To evaluate the accuracy of POS for CCHD in asymptomatic term newborns and to identify the missing cases. Subjects and Methods: This retrospective cohort study was performed in asymptomatic term newborns born from June 2016 to September 2017 at Hatyai Hospital. Central electronic medical records (including POS and echocardiograms) during birth hospitalization and subsequent medical records at 6 months after discharge were reviewed. Statistical Analysis Used: The diagnostic accuracy of POS for CCHD was assessed by using sensitivity and specificity (with 95% confidence interval [CI]). Results: A total of 7137 asymptomatic term newborns were enrolled. POS had a sensitivity of 42.86% (95% CI 9.90–81.59) and a specificity of 99.96% (95% CI 99.88–99.99). Nearly 57.14% (4 out of 7 cases of CCHD) constituted secondary target group. All the late diagnoses (3 cases) were of coarctation of the aorta (COA). The mortality rate of late detected CCHD was 33.3%. Conclusions: POS displayed low detection rate in secondary target group, particularly those with COA. POS decreased late detection of CCHD by 57.1%. The mortality rate of COA was high in late detection. It was found that the appropriate time span for POS follow-up should be up to 4 months.

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