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Year : 2018  |  Volume : 7  |  Issue : 4  |  Page : 254-258

Comparison of outcome of very-low-birth-weight babies with developed countries: A prospective longitudinal observational study

Department of Pediatrics, Punjab Institute of Medical Sciences, Jalandhar, Punjab, India

Correspondence Address:
Dr. Anuradha Bansal
Department of Pediatrics, Punjab Institute of Medical Sciences, Jalandhar, Punjab
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jcn.JCN_76_18

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Objective: The objective of this study was to compare the immediate outcome of very-low-birth-weight (VLBW) babies with developed countries. Materials and Methods: Design: This was a prospective observational longitudinal study. Setting: This study was conducted in Level II neonatal intensive care unit at a tertiary care center. Subjects: All live-born inborn babies with birth weight 401–1499 g or gestational age between 22 weeks 0 days and 31 weeks 9 days. Outcome: The key outcome was survival to discharge for VLBW babies. Results were compared to data from both developing and developed countries. Results: Of 183 babies enrolled in the study, 73.2% of babies were alive at initial disposition. The outcome (mortality and morbidity) was compared to data from Vermont Oxford Network, the National Institute of Child Health and Human Development as well as mortality data from developing countries. Mortality rates were lower or comparable to the data from developing countries (P > 0.05) but significantly higher than developed countries (P < 0.001). On the other hand, rates of survival with major morbidity were lower than developed countries (P < 0.001). Conclusion: This study provides a baseline database for evaluating the efficiency of perinatal services in a tertiary care center. Further, large-scale trials are needed to substantiate our findings and to study and compare the neurodevelopmental outcome of VLBW infants.

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