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CASE REPORT
Year : 2018  |  Volume : 7  |  Issue : 3  |  Page : 185-189

Transient hyperaldosteronism and neonatal hypertension: Case series and literature review


1 Peter Lougheed Centre, University of Calgary, Calgary, Canada
2 Foothills Medical Centre, University of Calgary and Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Canada

Correspondence Address:
Dr. Essa Hamdan Al Awad
Section of Neonatology, University of Calgary, Peter Lougheed Centre, 3500, 26th Ave., NE, Calgary, AB T1Y6J4
Canada
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jcn.JCN_57_18

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Neonatal hypertension is an uncommon but important problem in Neonatal Intensive Care Unit. The most common cause of neonatal hypertension is renovascular disease. In premature neonates, hypertension has been associated with the use of postnatal steroids, maternal history of hypertension, umbilical artery catheterization, acute kidney injury, and bronchopulmonary dysplasia (BPD). The exact mechanism of hypertension in BPD infants is unknown. We present a case series of premature infants with BPD and hypertension associated with transient hyperaldosteronism in the absence of any other cause for the elevated blood pressure. All infants responded to aldosterone antagonists. Transient hyperaldosteronism may have a role in the pathogenesis of hypertension associated with BPD.


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